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The device, produced by ordinary 3D printing and capable of being miniaturized, detects levels of the protein PARK7/DJ-1, which is associated with the disease. The study used samples of blood serum and cerebrospinal fluid.

A study by a group at the University of São Paulo reported in a scientific journal involved the construction of a database and models. Preliminary results are described in the article.

A memorandum of understanding was signed in Paris by the heads of FAPESP, ANRS and INSERM. Creation of Institut Pasteur de São Paulo, to be hosted by the University of São Paulo with more than 80 researchers, was also formalized in the French capital.

The new RIDCs will conduct research on biodiversity and climate change, antimicrobial resistance, the biology of bacteria and bacteriophages, theranostic medicine against cancer, and tropical agriculture’s carbon footprint.

The mechanism has resulted from evolution over millions of years to protect the buds that enable plants to survive fire. A study conducted in an environmental protection unit in São Paulo state (Brazil) can contribute to strategies for mitigating the effects of climate change.

Developed at the University of São Paulo, the device permits corrections to the dosage of the analgesic to improve its efficacy according to the patient’s profile and avoid toxic side effects or overdose.

Deletion of two genes, which in mice attenuated the action of the bacteria, made the immune response more exacerbated in broiler chicks. The findings reinforce the need for animal health and hygiene measures throughout the poultry production chain.

A lack of community involvement impairs fire control programs in the region known as MAP, between Madre de Dios (Peru), Acre (Brazil) and Pando (Bolivia).

This conclusion, presented by Brazilian researchers in the journal Scientific Reports, is based on a systematic review of clinical trials held to investigate the effect of strength training on blood pressure in hypertensive patients. All age groups benefited, but the positive effects were most evident in patients aged 50 or less.

Addition of rosmarinic acid at a mere 0.1% reduced the amount of sunscreen needed to protect the skin, increased the sun protection factor by more than 41% and combined photoprotection with antioxidant activity. The innovation would reduce the volume of chemical substances discharged into the environment.

The finding is from a longitudinal study conducted in Brazil. Analyzing data for high school students aged 13-18, it concluded that the problem affects girls more than boys and is associated with physical inactivity and low academic achievement.

A review of the literature shows that 15% of articles published between 1960 and 2021 focused on only ten species, while no articles at all were published on almost 40% of all species. Research efforts tend to be biased toward large-bodied animals and species native to wealthier countries, among other factors that should be taken into consideration when planning future studies, according to the authors.

The center will be hosted by the Federal University of Ceará and will focus on the use of the Internet of Things, big data, digital transformation and cutting-edge technology in prevention, diagnosis and low-cost therapies.

Experiments involving nematode worms conducted by researchers at the University of São Paulo showed that the benefits of physical activity to muscles are directly linked to processes occurring in mitochondria, the organelles that make energy for cells. Their findings offer possible routes for drug development.

Established by FAPESP and Embraer at the Aeronautical Technology Institute (ITA), ERC-AMF will conduct research on innovative topics with the potential to contribute to the competitiveness of Brazil’s aerospace industry.

Scientists at a FAPESP-supported research center combined substances extracted from fruit residues and egg white to package nanoparticles of anthocyanin, a plant pigment with antioxidant action. This nanoencapsulation prevents breakdown of the molecule and lets a larger amount reach the gut, where it is absorbed.

With the support of FAPESP and Banco Industrial do Brasil, the National Center for Research and Innovation in Mental Health (CISM) was launched at an event held on March 15.

A device developed at the University of São Paulo resembles the glucometer used by diabetics to measure blood sugar: when it comes into contact with the surface of a fruit or vegetable, it detects and quantifies any traces of carbendazim, a fungicide in widespread use in Brazil despite being banned.

Brazilian researchers identified the genes that make the industrial yeast strain Saccharomyces cerevisiae SA-1 resistant to fermentation inhibitors generated during sugarcane bagasse preprocessing. The discovery will be useful as a basis for metabolic engineering of the microorganism.

Fire destroyed 4,141 km² of forest and 6,484 km² of pasture and cropland between 2003 and 2019 in the area of Boca do Acre, Amazonas state, North Brazil, according to a recently published report. A year-by-year breakdown shows that the area affected by fire ranged from a low of 33 km² in 2011 to a high of 681 km² in 2019.

In a study conducted in São Paulo, Brazil, exercise training increased connectivity between the hypothalamus and sensory regions, accelerating satiety, for example.

France’s leading public-sector scientific research organization already has similar partnerships in the US, UK and Japan. FAPESP President Marco Antonio Zago expressed interest in supporting projects conducted at the center to be set up in São Paulo, Brazil, focusing on areas such as oceanography, biodiversity, and sustainability.

Rectors, vice-rectors, pro-rectors and heads of department at universities in São Paulo state established Rede Equidade as a force for formulating and promoting equity programs that take into account the links between gender and other differences and inequalities.

Annual production of NH3, the world’s most synthesized molecule, totals 1.2 million metric tons. Its successful use in fuel cells will boost demand.

Thin films of transition metal tungstate showed potential for use in water splitting reactions and other photoelectrocatalytic applications.

A study in rats analyzed neural rhythm in the prefrontal cortex and hippocampus with machine learning techniques. The results could guide future personalized treatments for psychiatric disorders.

Analysis conducted in Spain used a methodology developed by researchers at the State University of Campinas to detect many toxins simultaneously.

Researchers discuss 17 case studies conducted in the Americas, Asia-Pacific and Africa involving ways to implement integrated management of water, energy and food.

The unique image captured by researchers affiliated with the National Space Research Institute shows positive upward discharges produced by lightning rods and objects on nearby buildings competing to connect to the negative strike as it descended from the clouds. The photo was used to illustrate the cover of Geophysical Research Letters.

Machine learning tool measures how environmental variables such as humidity and solar radiation affect the amount of carbon captured in a given area.

A survey of news items on Brazilian deer published between 2011 and 2021 shows that most referred to habitat loss and poaching, but diseases transmitted by cattle and low reproductive efficiency were ignored as factors that can lead to species extinction. Lack of the right information can hinder conservation efforts.

Researchers at the State University of Campinas analyzed fossils found in Rio Grande do Sul, Brazil’s southernmost state, from dinosaurs that lived in the Late Triassic. The analysis showed that the three oldest dinosaurs lacked air sacs, which enabled pterosaurs to fly and are also found in present-day birds.

Significant changes in gut microbiota were observed in 42 men with coronary artery disease after they took 250 ml of red wine per day for five days a week over a period of three weeks.

Fatigue, breathlessness and other symptoms that may persist months after recovery from the infection may both favor sedentarism and be more frequent as a result of an inactive lifestyle, according to findings described by researchers at the University of São Paulo in an article in Scientific Reports.

In vitro tests were performed with cultured cells of glioblastoma, an aggressive type of cancer with few treatment options. The next step is to test the effects of the substances in normal nerve cells and animals.

The aim of the study was to analyze the virulence and antimicrobial resistance profile of the main agent of urinary tract infections.

The researchers analyzed data for more than 500 coffee farms in areas of Atlantic Rainforest and Cerrado, Brazil’s savanna-type biome, in 84 municipalities in the states of São Paulo and Minas Gerais.

Researchers followed 286 volunteers during a wave of COVID-19 in the Northeast region of Brazil in the first quarter of 2022. The number of cases fell among those who had been vaccinated with three doses, and they had more neutralizing antibodies than subjects who had not completed the vaccination scheme even when previously infected.

In a study involving mice, the scientists discovered that an avian variant of the TRPV1 receptor, which captures the burning sensation from pepper, can block chronic pain and provide protection against other stimuli in heart and brain cells.

An article by researchers at the Federal University of São Paulo argues that the analysis should consider not just the quantity but also the size and shape of plastic particles in water samples, as these variables influence the impact of plastic pollution on ecosystems.

When researchers at the State University of Campinas analyzed zika’s effects on normal and cancer cells, they discovered that while the virus can be used to treat the disease, it may trigger a harmful inflammatory process and damage the male reproductive system.

The study involved 28 volunteers diagnosed with sarcopenia, which is characterized by loss of muscle mass and strength.

The novel material was synthesized at the Center for Development of Functional Materials. The aim of the study was to combat the contamination caused by inappropriate disposal of pesticides and pharmaceuticals.

Technology developed at the University of São Paulo increases the precision of chemical analysis and reduces the use of expensive toxic solvents. The immediate focus was on parabens, potentially carcinogenic compounds used in industry as preservatives.

Brazilian researchers conducted preclinical trials involving mice to find the ideal dose and administration regime. The results suggest high daily doses of the probiotic are needed to obtain the benefit.

Representatives of the German higher education institution met with FAPESP’s senior executives to talk about their shared commitment to fostering research on sustainability.

The topic was raised by FAPESP President Marco Antonio Zago in his welcoming address to the São Paulo School of Advanced Science on the Bicentennial of Brazilian Independence, held on February 6-15 at Museu Paulista.

Wildcat prospecting has expanded faster since 2017 and occurs mainly on the Kayapó, Munduruku and Yanomami reservations, according to a study by scientists at Brazil’s National Space Research Institute.

First study to identify pixel and voxel organizational parameters in MRI scans of two different (albeit similar) benign tumors may contribute to development of more accurate, less invasive diagnosis.

A Brazilian study identified more than 74,000 active fires in the period. They were not mainly due to extreme drought, the foremost cause of the spate of forest fires seen in 2010. Half of the Amazon is typically vulnerable to fire in the two-month period analyzed. Human action was the main cause of the recent destruction.