Researchers at the University of Campinas in Brazil reveal the mechanisms whereby SARS-CoV-2 disrupts the regulation of inflammation, coagulation and blood pressure when it infects alveolar cells, responsible for gas exchange in the lungs.
Researchers analyzed the effects of wildfires on plant cover and soil quality in the last 40 years. The findings of the study show that the forest is highly vulnerable even in well-conserved areas far from the ‘deforestation arc’.
Sample collection is much easier and less invasive. Self-collecting is feasible, depending on the child’s age. Schools should reopen only with mass testing to keep track of asymptomatic cases, the researchers argue.
People with diseases such as rheumatoid arthritis and lupus are more likely to have heart attacks, angina, and strokes. A review of the scientific literature on the subject shows that regular exercise improves vascular function in these patients.
A multinational research group used data from São Paulo to perform calculations which suggest that even a minor reduction in the city’s mobility – equivalent to a rise from 45% to 50% in the social distancing index – correlates with a considerable fall in new infections and deaths after a few days.
A simple and affordable solution developed by researchers at the University of São Paulo and a Nigerian collaborator eliminates even multi-resistant bacteria. Clay, papaya seeds and banana peel are among the raw materials used by the group.
Butterflies are considered a key biological indicator of trends in the biome. The study quantified the contributions of landscape and climate variables to current species distribution patterns.
An electrical impedance tomography system developed by a Brazilian company enabled critical care staff at a hospital run by Harvard University to adopt individualized mechanical ventilation strategies and reduced the need for extracorporeal membrane oxygenation (ECMO) therapy
A study by researchers at São Paulo State University reinforces the idea that environmental and climate-related changes resulting from the Andean uplift triggered a revolution in the caste system of these paper wasps.
A clinical trial was conducted by researchers at the University of São Paulo with 240 patients who were given 200,000 IU of vitamin D3 on admission to hospital. The supplementation did not reduce length of stay or affect the proportion requiring intensive care.
Resonant-tunneling diodes are used in high-frequency oscillators, wave emitters and detectors, logic gates, photodetectors, and optoelectronic circuits. The study was a collaboration between Brazilian and German researchers.
A total of BRL 18.5 million will be allocated to funding for collaborative projects by researchers in the state of São Paulo with colleagues in other countries. Proposals must be submitted not later than July 10.
Researchers analyzed almost 30,000 RT-PCR tests on swabs from 4,269 players in 2020: 11.7% turned out positive. The rate was the same as among front-line health workers.
Researchers conducted the first large-scale survey of the microbiota present in the seamount’s ferromanganese crusts, describing bacteria and archaea involved in the nutrient cycle and formation of metals. Brazil has mineral exploration rights to the Rise, but mining there will have a major environmental impact.
A study led by researchers at the University of Campinas reinforces the need for prevention and follow-up treatment starting in early childhood to avoid development of this inflammatory disease of the gums.
The new cutoff values for a metric widely used by geriatricians, physical therapists and nutritionists are more accurate, facilitate early diagnosis and contribute to preventive treatment.
The law disciplines Brazil’s actions as a provider but not as a user of genetic resources from other countries, researcher Bráulio Dias noted during an online seminar held by FAPESP.
A study by the University of São Paulo has discovered that when macrophages engulf cells infected by the novel coronavirus, they begin producing excessive amounts of pro-inflammatory molecules, and their capacity to recognize and phagocytize dead cells is reduced twelvefold.
Brazilian researchers monitoring the population of metropolitan São Paulo have reported atypical cases in which SARS-CoV-2 continues to replicate in the organism for longer than the recommended isolation period.
The scientists detected incapacities related to gait timing and foot placement. Their discoveries serve as a basis for the development of an exercise protocol that mitigates the difficulty.
By means of specific biomarkers, a diagnostic test developed by the Brazilian startup Onkos shows whether a lump in the gland is benign or malignant, reducing the risk of unnecessary surgery.
Brazilian researchers treated cells infected by SARS-CoV-2 with compounds produced by gut microbiota from dietary fiber. The intervention did not mitigate viral replication but reduced expression of a gene that plays a key role in viral entry into cells and a receptor involved in the inflammatory process.
In an online seminar hosted by FAPESP, researchers from Brazil, the United States and France analyzed the impact of the pandemic on educational inequality.
Luciferin-luciferase system developed in collaboration with Japanese researchers produces brighter and longer-lasting far red light. The innovation can be used to image cells and tissues for diagnosis and biomedical research.
Researchers analyzed socioeconomic and environmental indicators for the 180 municipalities in the mega-region around São Paulo state capital, detecting environmental inequity and dependency.
Brazilians are working in more than 60 scientific fields in over 50 German cities. An online event hosted by the Brazilian Embassy in Berlin featured researchers and representatives of institutions.
Laboratory trial by Butantan Institute in partnership with the University of São Paulo involved inoculation of variants P.1 and P.2 into cultured cells containing blood serum from vaccinated subjects. The results were satisfactory, according to the researchers.
The technology uses ultraviolet-C, which can inactivate the novel coronavirus. Startup BioLambda was supported by FAPESP and partnered with the Albert Einstein Jewish-Brazilian Hospital in São Paulo.
Brazilian researchers tested the capacity of different materials to produce sensors for the detection of PCA3, a gene that is overexpressed in prostate cancer. The technique can also be used to diagnose infectious diseases, including COVID-19.
In a study of the effects of cigarette smoking on exacerbation of the disease, scientists at a FAPESP-supported research center identified a novel pathway in the inflammatory process relating to bone damage.
Published by an Anglo-Brazilian epidemiological research center, the study revealed that in only seven weeks SARS-CoV-2 lineage P.1 became the most prevalent strain of the virus in Manaus. Analysis of more than 900 samples from patients diagnosed in the period pointed to a higher viral load.
Blood plasma from COVID-19 convalescents was tested against Brazilian variant isolates obtained from patients diagnosed in Manaus. The study also assessed the effectiveness of plasma from volunteers immunized with CoronaVac.
In Araraquara, state of São Paulo, researchers detected the P.1 variant in 93% of samples from patients diagnosed at a primary healthcare facility in the first two months of the year.
Developed by researchers at the University of São Paulo, the non-invasive methodology facilitates identification of immature or poor-quality seeds without destroying them or creating residues.
In a study conducted at the University of São Paulo, researchers used infrared laser irradiation to accelerate the activity of enzymes immobilized on gold nanoparticles. The technique could have biomedical and industrial applications.
Study conducted at University of Campinas in collaboration with University of Michigan explains nanoscale physics of this manmade material in article published in Science Advances.
Open-access repository established to facilitate research on the disease holds anonymized data including clinical examinations and laboratory test results from 485,000 patients processed by five institutions.
Study suggests that replacing native vegetation with pasture or crops increases competition among microorganisms, favoring those with antimicrobial resistance genes. Brazilian scientists advocate more research to find out whether bacteria can migrate to food and reach humans.